Skip to main content

Official Journal of the Japan Wood Research Society

Journal of Wood Science Cover Image

Chemical constituents ofInonotus obliquus II: a new triterpene, 21,24-cyclopentalanosta-3β,21,25-triol-8-ene from sclerotium


A new lanostane-type triterpene with a cyclopentanol partial structure in the side chain was isolated from the sclerotium of the wood rotting fungusInonotus obliquus along with four known compounds: lanosterol, inotodiol, trametenolic acid, and 3β-hydroxy-8,24-dienlanosta-21,23-lactone. The new compound was determined to be 21,24-cyclopentalanosta-3β,21,25-triol-8-ene by spectroscopic analyses.


  1. 1.

    Yamaguchi T (1992) Basidiosphore discharge ofFuscoporia obliqua (in Japanese). Ringakkai Hokkaido Sibu Ronbunshu 40:30–32

    Google Scholar 

  2. 2.

    Molitoris HP (1994) Mushrooms in medicine. Folia Microbiol 39(2):91–98

    CAS  Article  Google Scholar 

  3. 3.

    Maret S (1991) Fungi in Khanty folk medicine. J Ethnopharmacol 31:175–179

    Article  Google Scholar 

  4. 4.

    Mizuno T, Zhuang C, Abe K, Okamoto H, Kiho T, Ukai S, Leclerc S, Meijer L (1996) Studies on the host-mediated antitumor polysaccharides. Part XXVII. Mushroom Sci Biotechnol 3(2):53–60

    Google Scholar 

  5. 5.

    Kahlos K, Kangas L, Hiltunen R (1987) Antitumour activity of some compounds and fractions from ann-hexane extract ofInonotus obliquus. Acta Pharm Fenn 96:33–40

    CAS  Google Scholar 

  6. 6.

    Shin Y, Tamai Y, Terazawa M (2000) Chemical constituents ofInonotus obliquus I. Eurasian J For Res 1:43–50

    CAS  Google Scholar 

  7. 7.

    Kahlos K, Schantz MV, Hiltunen R (1984) 3β-Hydroxy-lanosta-8,24-dien-21-al, a new triterpene fromInonotus obliquus. Acta Pharm Fenn 92:197–198

    Google Scholar 

  8. 8.

    Kahlos K, Hiltunen R (1986) Two oxygenated lanostane type triterpenes fromInonotus obliquus. Acta Pharm Fenn 95:71–76

    CAS  Google Scholar 

  9. 9.

    Kahlos K (1986) 3β,22-Dihydroxy-lanosta-8,24-dien-7-one, a new 7-keto compound fromInonotus obliquus. Acta Pharm Fenn 95:113–117

    CAS  Google Scholar 

  10. 10.

    Kahlos K, Hiltunen R (1986) 3β,22-Dihydroxy-lanosta-7,9(ll),24-trien, a new minor compound fromInonotus obliquus. Planta Med 52:495–496

    Article  Google Scholar 

  11. 11.

    Kahlos K, Kangas L, Hiltunen R (1986) Antitumour tests of inotodiol from the fungus.Inonotus obliquus. Acta Pharm Fenn 95:173–177

    Google Scholar 

  12. 12.

    Gninenko YI (1995) On the problem of the stock of the fungusInonotus obliquus (PERS.)Pil.F. sterilis(VAN)NIKOL: in northern and central Kazakhstan. Rastitel Nye Resursy 31(4):37–40

    Google Scholar 

  13. 13.

    Burczyk J, Gawrin A, Slotwinska M (1996) Antimitotic activity of aqueous extracts ofInonotus obliquus. Bull Chim Farmaceut Anno 135:306–309

    CAS  Google Scholar 

  14. 14.

    Kahlos K, Lesnau A, Lange W, Lindequist U (1996) Preliminary tests of antiviral activity of twoInonotus obliquus strains. Fitoterapia 67:344–347

    Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Yusoo Shin.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Shin, Y., Tamai, Y. & Terazawa, M. Chemical constituents ofInonotus obliquus II: a new triterpene, 21,24-cyclopentalanosta-3β,21,25-triol-8-ene from sclerotium. J Wood Sci 47, 313–316 (2001).

Download citation

Key words

  • Inonotus obliquus
  • Sclerotium
  • Antitumor
  • Lanostane type
  • Triterpene