Skip to main content
Journal of Wood Science

Official Journal of the Japan Wood Research Society

Download PDF
  • Note
  • Published:

Proliferating effect of extracts from woods and fungi on rat vibrissa dermal papilla cells

Journal of Wood Science volume 47, pages 410–413 (2001)Cite this article

Abstract

Hair growth is a highly regulated cyclical process. Three distinct phases have been defined for the mammalian cycle: anagen (growing phase), catagen (regression phase), and telogen (resting phase). Although little is known about the mechanism that regulates the hair cycle, it is believed that dermal papillae (DP) derived from mesenchymal cells play an essential role in controlling the established hair follicle and hair cycle. The purpose of this investigation was to find the components of woods and fungi that exert a proliferative activity on DP cells. Results show that the fungus YL161 (ethyl acetate extract, 1ppm),Agaricus blazei (ethyl acetate extract, 0.1 ppm), and the bark ofCamptotheca cuminata (methanol extract of bark, 0.1 ppm) exhibit higher growth-promoting activity than pentadecanoic acid. These components that have a proliferative effect on DP cells may be useful hair growth-stimulating materials and can be used to understand the mechanism of hair growth.

References

  1. Albert M, Kligman MD (1959) The human hair cycle. J Invest Dermatol 33:307–316

    Article  Google Scholar 

  2. Herman BC (1954) Growth of hair. Physiol Rev 34:113–126

    Article  Google Scholar 

  3. Hugh G (1998) Nutritional and hormonal regulation of hair follicle growth and development. Proc Nutr Soc 57:195–205

    Article  Google Scholar 

  4. Oliver RF (1970) The induction of hair follicle formation in the adult hooded rat by vibrissa dermal papillae. J Embryol Exp Morphol 23:219–236

    PubMed  CAS  Google Scholar 

  5. Jahoda CAA, Horne KA, Oliver RF (1984) Induction of hair growth by implantation of cultured dermal papilla cells. Nature 311:560–562

    Article  CAS  PubMed  Google Scholar 

  6. Arase S, Sadamoto Y, Katoh S, Urano Y, Takeda K (1990) Co-culture of human hair follicles and dermal papillae in a collagen matrix. J Dermatol 17:667–676

    Article  CAS  PubMed  Google Scholar 

  7. Ibrahim L, Wright EA (1982) A quantitative study of hair growth using mouse and rat vibrissal follicles: dermal papilla volume determines hair volume. J Embryol Exp Morphol 77:209–224

    Google Scholar 

  8. Uno H (1991) Quantitative models for the study of hair growth in vivo. Ann NY Acad Sci 642:107–127

    Article  CAS  PubMed  Google Scholar 

  9. Elliott K, Stephenson TJ, Andrew GM (1999) Differences in hair follicle dermal papilla volume are due to extracellular matrix volume and cell number: implications for the control of hair follicle size and androgen responses. J Invest Dermatol 113:873–877

    Article  CAS  PubMed  Google Scholar 

  10. Tien M, Kirk TK (1988) Lignin peroxidase ofPhanerochaete chrysosporium. Methods Enzymol 161:238–249

    Article  CAS  Google Scholar 

  11. Yokoyama D (1999) Characteristics and problems of evaluation methods for hair growing effect (in Japanese). Fragrance J 27:50–56

    CAS  Google Scholar 

  12. Danilenko DM, Ring BD, Pierce GF (1996) Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapy. Mol Med Today 2:460–467

    Article  CAS  PubMed  Google Scholar 

  13. Kurt SS, Nickolas JC, Kenneth JE, Joel SG, Jose RP, Satish P, Stephen MP (1996) Hair follicle growth controls. Dermatol Clin 14:543–558

    Article  Google Scholar 

  14. Ebina T, Fujimiya Y (1998) Antitumor effect of a peptide-glucan preparation extracted fromAgaricus blazei in a double-grafted tumor system. Biotherapy 11:259–265

    Article  CAS  PubMed  Google Scholar 

  15. Fujimiya Y, Suzuki Y, Katakura R, Ebina T (1999) Tumor-specific cytocidal and immunopotentiating effects of relatively low molecular weight products derived from the basidiomycete,Agaricus blazei Murill. Anticancer Res 19:113–118

    PubMed  CAS  Google Scholar 

  16. Kulick MI (1988) Topical minoxidil: its use in treatment of male pattern baldness. Ann Plast Surg 21:273–275

    Article  CAS  PubMed  Google Scholar 

  17. Olsen EA (1989) Treatment of androgenetic alopecia with topical minoxidil. Resident Staff Physician 35:53–69

    Google Scholar 

  18. Kaufman KD, Olsen EA, Whiting D (1998) Finasteride in the treatment of men with androgenetic alopecia. J Am Acad Dermatol 39:578–589

    Article  CAS  PubMed  Google Scholar 

  19. Mary AM, Michael HF, Anthony SM (1989) Serve toxicity from ingestion of a topical minoxidil preparation. Am J Emerg Med 7:419–421

    Article  Google Scholar 

  20. Nickel JC, Fradet Y, Boake RC, Pommerville PJ, Perreault JP, Afridi SK, Elhilali MM (1996) Efficacy and safety of finasteride therapy for benign prostatic hyperplasia: results of a 2-year randomized controlled trial (the PROSPECT study). Can Med Assoc J 155:1251–1259

    CAS  Google Scholar 

  21. Wilton L, Pearce G, Edet E, Freemantle S, Stephens MDB, Mann RD (1996) The safety of finasteride used in benign prostatic hypertrophy: a non-interventional obsevational cohort study in 14722 patients. Br J Urol 78:379–384

    Article  CAS  PubMed  Google Scholar 

  22. Arakawa T, Emoto K, Utsunomiya S, Hagiwara Y, Shimizu T (1962) Effect of swertinogen on hair growth with special reference to its activities on skin function. Tokushima J Exp Med 9:37–59

    PubMed  CAS  Google Scholar 

  23. Paus R, Heinzelmann T, Schultz K-D, Furkert J, Fechner K, Czarnetzki BM (1994) Hair growth induction by substance-P. Lab Invest 71:134–140

    PubMed  CAS  Google Scholar 

  24. Takahashi T, Kamiya T, Hasegawa A, Yokoo Y (1999) Procyanidin oligomers selectively and intensively promote proliferation of mouse hair epithelial cells in vitro and activate hair follicle growth in vivo. J Invest Dermatol 112:310–316

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Forest Products, Faculty of Agriculture, Kyushu University, 812-8581, Fukuoka, Japan

    Keisuke Towatari, Ryuichiro Kondo & Kokki Sakai

Authors
  1. Keisuke Towatari
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ryuichiro Kondo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kokki Sakai
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ryuichiro Kondo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Towatari, K., Kondo, R. & Sakai, K. Proliferating effect of extracts from woods and fungi on rat vibrissa dermal papilla cells. J Wood Sci 47, 410–413 (2001). https://doi.org/10.1007/BF00766795

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00766795

Key words