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Official Journal of the Japan Wood Research Society

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Lignans ofChamaecyparis obtusa


Heartwood ofChamaecyparis obtusa contains significant amounts of a dibenzylbutyrolactone lignan, hinokinin (8). This investigation demonstrated that the contents of 8 and a norlignan, hinokiresinol (12), were higher in the heartwood region than in the sapwood, indicating their nature of being heartwood extractives. Eleven lignans — xanthoxylol (1), 7-oxohinokinin (2), savinin (3), dihydrosesamin (4), isoactifolin (5), sesamin (6), piperitol (7), hinokinin (8), pluviatolide (9), haplomyrfolin (10), and rnatairesinol (11) — were isolated from young shoots ofChamaecyparis obtusa cv. Breviramea. Eight lignans (1, 2, 4, 5, 7, 9,10, and11) were isolated from this plant for the first time. Chiral high-performance liquid Chromatographie analysis showed that8, 9, 10, and11, were found to be levorotatory and optically pure (>99% e.e.). Based on the chemical structures of the isolated lignans, possible biosynthetic pathways of8 are discussed.


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Correspondence to Toshiaki Umezawa.

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Takaku, N., Choi, D., Mikame, K. et al. Lignans ofChamaecyparis obtusa . J Wood Sci 47, 476–482 (2001).

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Key words

  • Lignan
  • Stereochemistry
  • Chamaecyparis obtusa
  • Chamaecyparis obtusa cv. Breviramea
  • Heartwood