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Official Journal of the Japan Wood Research Society

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Phenolic constituents ofTaxus cuspidata I: lignans from the roots

Abstract

The phenolic constituents of the roots ofTaxus cuspidata (Japanese yew) were investigated. Four lignans, [(+)-taxiresinol (1), (+)-lariciresinol (2), (−)-secoisolariciresinol (3), and (+)-pinoresinol (4)] were isolated and identified. The assignment of proton and carbon atoms for the lignans were finally solved by one- and twodimensional-nuclear magnetic resonance spectra. The enantiomeric excess of these lignans were determined by chiral high-performance liquid Chromatographic analyses. (+)-Lariciresinol and (−)-secoisolariciresinol were optically pure; (+)-taxiresinol was also suggested to be optically pure, although (+)-pinoresinol was not (77% enantiomeric excess).

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Correspondence to Fumio Kawamura.

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Kawamura, F., Kikuchi, Y., Ohira, T. et al. Phenolic constituents ofTaxus cuspidata I: lignans from the roots. J Wood Sci 46, 167–171 (2000). https://doi.org/10.1007/BF00777366

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Key words

  • Taxus cuspidata root
  • Lignan
  • (+)-Taxiresinol
  • (+)-Pinoresinol
  • Enantiomer