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Ginkgolide production in relation to organogenesis inGinkgo biloba

Abstract

The contents of diterpenoids, ginkgolides A, B, and C, in seeds, embryos, and plantlets ofGinkgo biloba were analyzed to clarify the relations between organogenesis and terpene contents inG. biloba. There is so far no published report on the contents and changes in such terpenes in seeds and very young plantlets ofG. biloba. Ginkgolides were present in seeds and embryos. Plantlets cultured in both the dark and under illumination contained substantial amounts of ginkgolides, more abundant than in seeds and embryos. It is concluded that ginkgo yields ginkgolides in its early stage of development regardless of light.

References

  1. 1.

    Nakanishi K (1967) The ginkgolides. Pure Appl Chem 14:89–113

    CAS  Article  PubMed  Google Scholar 

  2. 2.

    Okabe K, Yamada K, Yamamura S, Takada S (1967) Ginkgolides. J Chem Soc (C) 21:2201–2206

    Google Scholar 

  3. 3.

    Braquet P (1987) The ginkgolides: potent platelet-activating factor antagonists isolated fromGinkgo biloba L.: chemistry, pharmacology and clinical applications. Drugs Future 12:643–699

    Article  Google Scholar 

  4. 4.

    Corey EJ, Kang MC, Desai MC, Ghosh AK, Houpis IN (1988) Total synthesis of (±)-ginkgolide B. J Am Chem Soc 110:649–651

    CAS  Article  Google Scholar 

  5. 5.

    Chauret N, Carrier J, Mancini M, Neufeld R, Weber M, Archambault J (1991) Gas chromatographic-mass spectrometric analysis of ginkgolides produced byGinkgo biloba cell culture. J Chromatogr 588:281–287

    CAS  Article  Google Scholar 

  6. 6.

    Huh H, Staba EJ (1993) Ontogenic aspects of ginkgolide production inGinkgo biloba. Planta Med 59:232–239

    CAS  Article  PubMed  Google Scholar 

  7. 7.

    Jeon MH, Sung SH, Huh H, Kim YC (1995) Ginkgolide B production in cultured cells derived fromGinkgo biloba L. leaves. Plant Cell Rep 14:501–504

    CAS  Article  PubMed  Google Scholar 

  8. 8.

    Van Beek TA, Lelyveld GP (1992) Concentration of ginkgolides and bilobalide inGinkgo biloba leaves in relation to the time of year. Planta Med 58:413–416

    Article  PubMed  Google Scholar 

  9. 9.

    Flesch V, Jacque M, Cosson L, Teng BP, Petiald V, Balz JP (1992) Relative importance of growth and light level on terpene content ofGinkgo biloba. Phytochemistry 31:1941–1945

    CAS  Article  Google Scholar 

  10. 10.

    Inoue H, Sato S, Kamoda S, Terada T, Saburi Y (1996) Hormonal responses of petioles and embryos inGinkgo biloba cultures. Bull Tokyo Univ For 96:119–123

    Google Scholar 

  11. 11.

    Linsmaier EM, Skoog F (1965) Organic growth requirements of tobacco tissue cultures. Physiol Plant 18:100–127

    CAS  Article  Google Scholar 

  12. 12.

    Chinn E, Silverthorne J (1993) Light-dependent chloroplast development and expression of a light-harvesting chlorophyll a/b-binding protein gene in the gymnospermGinkgo biloba. Plant Physiol 103:727–732

    CAS  Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Hiroki Inoue.

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Inoue, H., Kamoda, S., Terada, T. et al. Ginkgolide production in relation to organogenesis inGinkgo biloba . J Wood Sci 44, 375–378 (1998). https://doi.org/10.1007/BF01130450

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Key words

  • Ginkgo biloba
  • Ginkgolide
  • Organogenesis