- Note
- Published:
Antimicrobial activity of heartwood components of sugi (Cryptomeria japonica) against several fungi and bacteria
Journal of Wood Science volume 52, pages 552–556 (2006)
Abstract
Methanol extract of sawdust of sugi (Cryptomeria japonica) heartwood was fractionated with toluene and n-hexane to give solvent-soluble and solvent-insoluble fractions. The n-hexane-soluble fraction showed the most inhibition activity among the fractions against phytopathogenic microorganisms, namely Fusarium oxysporum, Phytophthora capsici, Pythium splendens, and Ralstonia solanacearum. Sandaracopimarinol and ferruginol, isolated from the n-hexane-soluble fraction, showed moderate antifungal activity against the three fungi and strong antibacterial activity against R. solanacearum. The content of sandaracopimarinol (7.07 g/kg based on the dried sawdust) in the heartwood was about twice that of ferruginol. Sandaracopimarinol and ferruginol strongly inhibited the growth of Gram-positive bacteria but did not show inhibitory action against Gram-negative bacteria except for R. solanacearum. The antibacterial effect of sandaracopimarinol was first found in the present study and was stronger than that of ferruginol.
References
Morita S, Yatagai M, Ohira T (1991) Antimite and antifungal activities of the hexane extractives from Yakusugi bogwood (in Japanese). Mokuzai Gakkaishi 37:352–357
Morita S, Hidaka T, Yatagai M (1997) Antifungal components of the extractives of Yakusugi (Cryptomeria japonica D. Don) (in Japanese). Mokuzai Hozon 23:61–69
Nakajima K, Yoshimoto T, Fukuzumi T (1980) Substances inhibiting growth of shiitake mycelium in sugi wood (Cryptomeria japonica D. Don) (in Japanese). Mokuzai Gakkaishi 26:698–702
Kawachi S, Meguro S, Inada S (1991) Cultivation of shiitake (Lentinus edodes) on wood-meal medium of Cryptomeria japonica. Inhibitory effect of ferruginol on mycelial growth (in Japanese). Mokuzai Gakkaishi 37:971–975
Matsui T, Matsushita Y, Sugamoto K, Ogawa K, Kimiyama A, Muta S (2001) Mycelial growth inhibition of shiitake (Lentinula edodes) by several terpenoids isolated from sugi (Cryptomeria japonica) wood (in Japanese). Mokuzai Gakkaishi 47:58–62
Kofujita H, Fujino Y, Sasaki T, Hasebe M, Ota M, Suzuki K (2001) Antifungal activity of the bark of Cryptomeria japonica and its relevant components (in Japanese). Mokuzai Gakkaishi 47:479–486
Kofujita H, Ota M, Takahashi K, Kawai Y, Hayashi Y (2002) A diterpene quinone from the bark of Cryptomeria japonica. Phytochemistry 61:895–898
Arihara S, Umeyama A, Bando S, Imoto S, Ono M, Yoshikawa K (2004) Three new sesquiterpenes from the black heart wood of Cryptomeria japonica. Chem Pharm Bull 52:463–465
Cheng SS, Lin HY, Chang ST (2005) Chemical composition and antifungal activity of essential oils from different tissues of Japanese cedar (Cryptomeria japonica). J Agric Food Chem 53:614–619
Lee CK, Chang MH (2000) The chemical constituents from the heartwood of Eucalyptus citriodora. J Chinese Chem Soc 47:555–560
Matsui T, Yoshida K, Nakayama N, Mizutani M (1991) Isolation and chemical structures of constituents of steam exploded Sugi (Cryptomeria japonica D. Don) wood (in Japanese). Bull Fac Eng Miyazaki Univ 37:33–39
Matsumoto T, Ohsuga Y, Harada S, Fukui K (1977) Synthesis of taxodione, royleanone, cryptojaponol, and methyl 11-hydroxy-12-methoxy-7-oxoabieta-8,11,13-trien-18-oate. Bull Chem Soc Jpn 50:266–272
Sogabe A, Kinjo K, Abe F, Yamauchi T, Yaga S (2000) Termiticidal substances from the heartwood of Cryptomeria japonica (in Japanese). Mokuzai Gakkaishi 46:124–131
Aoyama M, Mori M, Okumura M, Doi S, Anetai M (1997) Antifungal activity of 2′,6′-dihydroxy-4′-methoxyacetophenone and related compounds. Mokuzai Gakkaishi 43:108–111
The Japanese Society of Chemotherapy (1981) Method for in vitro determination of bacterial susceptibility (minimum inhibitory concentration; MIC) to antibacterial agents (in Japanese). Chemotherapy 29:76–79
Kubo I, Muroi H, Himejima M (1992) Antibacterial activity of totarol and its potentiation. J Nat Prod 55:1436–1440
Haraguchi H, Oike S, Muroi H, Kubo I (1995) Mode of antibacterial action of totarol, a diterpene from Podocarpus nagi. Planta Medica 62:122–125
Nicolson K, Evans G, O’Toole PW (1999) Potentiation of methicillin activity against methicillin-resistant Staphylococcus aureus by diterpenes. FEMS Microbiol Lett 179:233–239.
Ashitani T, Ujike M, Nagahama S, Ueno T, Sakai K (2001) Characterization of sugi (Cryptomeria japonica) bark extracts (in Japanese). Mokuzai Gakkaishi 47:276–281
Kobayashi K, Nishino C, Fukushima M, Shiobara Y, Kodama M (1988) Antibacterial activity of pisiferic acid and its derivatives against Gram-negative and-positive bacteria. Agric Biol Chem 52:77–83
Muhammad I, Mossa JS, El-Feraly FS (1996) Additional antibacterial diterpenes from the bark of Juniperus procera. Phytother Res 10:604–607
Evans GB, Furneaux RH, Gravestock MB, Lynch GP, Scott GK (1999) The synthesis and antibacterial activity of totarol derivatives. Part 1: modifications of ring-C and pro-drugs. Bioorg Med Chem 7:1953–1964
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Matsushita, Yi., Hwang, YH., Sugamoto, K. et al. Antimicrobial activity of heartwood components of sugi (Cryptomeria japonica) against several fungi and bacteria. J Wood Sci 52, 552–556 (2006). https://doi.org/10.1007/s10086-005-0793-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10086-005-0793-9