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Journal of Wood Science

Official Journal of the Japan Wood Research Society

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Antioxidant activity and constituents of extracts from the root of Garcinia multiflora

Journal of Wood Science volume 54, pages 383–389 (2008)Cite this article

Abstract

The methanolic extract of the root of Garcinia multiflora and its derived soluble fractions, namely those soluble in ethyl acetate (EtOAc), n-butanol, and water, were screened for their antioxidant activities. Among them, the EtOAc-soluble fraction exhibited the highest scavenging activity against the 1,1-dipheny1,2-picrylhydrazyl radical, the highest superoxide radical scavenging activity, and the strongest reducing power. In addition, according to the bioactivity-guided isolation, 26 specific phytocompounds, including 3 aromatics, 3 benzophenones, 3 flavonoids, 3 isocoumarins, 1 phloroglucinol, 6 steroids, and 7 xanthones, were isolated from the EtOAc-soluble fraction and identified. Of these, 2,4,3′,4′-tetrahydroxy-6-methoxybenzophenone and 1,3,6,7-tetrahydroxyxanthone were found to be the major bioactive constituents, present in the crude extract in concentrations of 3.9 and 15.6 mg/g, respectively. These two compounds had similar antioxidant activities to (+)-catechin, a well-known antioxidant.

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Authors and Affiliations

  1. Department of Forestry, National Chung-Hsing University, Taichung, 402, Taiwan

    Jyh-Horng Wu & Sheng-Yang Wang

  2. School of Forestry and Resource Conservation, National Taiwan University, Taipei, 106, Taiwan

    Yu-Tang Tung & Shang-Tzen Chang

  3. Department of Chemistry, National Taiwan University, Taipei, 106, Taiwan

    Chiou-Fung Chyu & Shih-Chang Chien

  4. Department of Chemistry, National Taiwan University, Taipei, 106, Taiwan

    Yueh-Hsiung Kuo

  5. Agricultural Biotechnology Research Center, Academia Sinica, Taipei, 115, Taiwan

    Yueh-Hsiung Kuo

  6. Tsuzuki Institute for Traditional Medicine, College of Pharmacy, China Medical University, Taichung, 404, Taiwan

    Yueh-Hsiung Kuo

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  1. Jyh-Horng Wu
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Correspondence to Yueh-Hsiung Kuo.

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Wu, JH., Tung, YT., Chyu, CF. et al. Antioxidant activity and constituents of extracts from the root of Garcinia multiflora . J Wood Sci 54, 383–389 (2008). https://doi.org/10.1007/s10086-008-0961-9

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  • DOI: https://doi.org/10.1007/s10086-008-0961-9

Key words

  • Antioxidant
  • Bioactivity-guided isolation
  • Garcinia multiflora
  • Phytocompound
  • Reactive oxygen species