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Journal of Wood Science

Official Journal of the Japan Wood Research Society

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Chemical constituents from Gmelina arborea bark and their antioxidant activity

Journal of Wood Science volume 54, pages 483–489 (2008)Cite this article

Abstract

Gmelina arborea Roxb. is a fast-growing species and is known to have been used in traditional Indian medicine. Chemical constituents from the bark have not been reported, although some chemical constituents from part of this plant (heartwood, leaf, and root) are known. In this study, the bark meal was successively extracted with acetone and methanol. Fractionation of the acetone extract with n-hexane, diethyl ether, and ethyl acetate and subsequent chromatographic separation of the fractions led to the isolation of four compounds. The diethyl ether-soluble fraction yielded tyrosol [2-(4-hydroxyphenyl)ethanol] (1); (+)-balanophonin (2), an 8-5′ neolignan, with opposite optical rotation to known (−)-balanophonin; and gmelinol (3), a known lignan. The ethyl acetate-soluble fraction afforded a new phenylethanoid glycoside to the best of our knowledge, which was identified as (−)-p-hydroxyphenylethyl[5′″-O-(3,4-dimethoxycinnamoyl)-β-d-apiofuranosyl(1′" → 6′)]-β-d-glucopyranoside (4). From the methanol extract, two known compounds, 2,6-dimethoxy-p-benzoquinone (5) and 3,4,5-trimethoxyphenol (6), were isolated and identified. The 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay of the identifi ed compounds indicated that 3,4,5-trimethoxyphenol (6) exhibited moderate activity.

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Authors and Affiliations

  1. Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kagawa, 761-0795, Japan

    Syamsul Falah, Takeshi Katayama & Toshisada Suzuki

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  1. Syamsul Falah
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  2. Takeshi Katayama
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  3. Toshisada Suzuki
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Corresponding author

Correspondence to Takeshi Katayama.

Additional information

Part of this report was presented at the 57th and 58th Annual Meetings of the Japan Wood Research Society, Hiroshima and Tsukuba, August 2007 and March 2008, respectively

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Falah, S., Katayama, T. & Suzuki, T. Chemical constituents from Gmelina arborea bark and their antioxidant activity. J Wood Sci 54, 483–489 (2008). https://doi.org/10.1007/s10086-008-0983-3

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