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Official Journal of the Japan Wood Research Society

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Antihyperglycemic effects of Japanese maple Acer amoenum leaf extract and its constituent corilagin

Journal of Wood Science volume 56, pages 507–512 (2010)Cite this article

Abstract

The antihyperglycemic effects of the leaves of Acer amoenum and purification and identification of an active compound were investigated. In screening experiments for α-glucosidase inhibitory activity, methanolic extracts of A. amoenum leaves showed potent inhibitory action. This extract showed antihyperglycemic effects in sucrose-loaded mice. Fractionation of the crude extract gave the active compound corilagin [β-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose] by spectroscopic analysis. This is the first report about the possibility of novel utilization of the Japanese maple tree as a source of compounds for prevention or treatment of diabetes mellitus.

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Authors and Affiliations

  1. Laboratory of Nutraceuticals and Functional Foods Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato-ku, Tokyo, 108-8477, Japan

    Atsushi Honma, Tomoyuki Koyama & Kazunaga Yazawa

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  1. Atsushi Honma
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  2. Tomoyuki Koyama
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  3. Kazunaga Yazawa
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Correspondence to Tomoyuki Koyama.

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Honma, A., Koyama, T. & Yazawa, K. Antihyperglycemic effects of Japanese maple Acer amoenum leaf extract and its constituent corilagin. J Wood Sci 56, 507–512 (2010). https://doi.org/10.1007/s10086-010-1130-5

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  • DOI: https://doi.org/10.1007/s10086-010-1130-5

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