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Journal of Wood Science

Official Journal of the Japan Wood Research Society

Table 3 Effect of fruit oil of L. cubeba on pentobarbitone-induced sleeping time in mice

From: Neuropharmacological activities of fruit essential oil from Litsea cubeba Persoon

Treatment (mg/kg)

Mean sleeping time ± SD (min)

Control saline (20)

34.4 ± 6.8

Fruit oil (100)

41.3 ± 12.8*

Fruit oil (300)

72.5 ± 19.8***

Fruit oil (500)

89.3 ± 31.2**

Zolpidem hemitartrate (0.3)

46.8 ± 3.39*

  1. All animals were treated with pentobarbitone sodium (45 mg/kg, i.p.) 60 min after oral administration of vehicle and fruit oil of L. cubeba
  2. * P < 0.05, ** P < 0.01 compared with vehicle-treated controls
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