Skip to main content

Official Journal of the Japan Wood Research Society

Table 4 Effects of fruit essential oil of L. cubeba and trazodone hydrochloride on mouse behavior in the elevated plus-maze test

From: Neuropharmacological activities of fruit essential oil from Litsea cubeba Persoon

Treatment

(mg/kg, p.o.)

Time spent in open arms (s)

Number of entries into open arms (times)

Control

9.72 ± 6.67

10.38 ± 8.70

Fruit oil (100)

18.73 ± 9.55

12.75 ± 9.98

Fruit oil (300)

28.07 ± 8.46**

18.43 ± 8.75

Fruit oil (500)

36.55 ± 11.65**

25.75 ± 11.51*

Trazodone hydrochloride (10)

28.86 ± 10.31**

21.63 ± 14.91*

  1. Data are presented as mean ± SD from 10 animals. Observations were made 60 min following the oral administration of vehicle (control) or fruits oil of L. cubeba
  2. P < 0.05 compared with vehicle-treated controls. * P < 0.05, ** P < 0.01, compared with vehicle-treated controls