Journal of Wood Science

Official Journal of the Japan Wood Research Society

Table 1 Optimization of the Knoevenagel–Doebner reaction conditions under (NH₄)₂SO₄

From: Synthesis of highly deuterated coniferyl alcohol for silencing of NMR signals in the resulting dehydrogenative polymer


Entry	(NH₄)₂SO₄ (eq.)	Pyridine (mL)^b	Temp. (°C)	Yield (%)^c
1	–	3.0	80	14
2	0.5	3.0	80	35
3	0.1	6.0	80	27
4	0.5	1.0	80	80
5	0.5	1.0	70	99
6	0.5	1.0	90	83

^aReaction temperature; ^b Volume to 1 mmol vanillin; c GC yield

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